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Ionis, Novartis' key experimental heart drug fails in late-stage trial

Reuters · Healthcare · 2026-09-04

Ionis, Novartis' key experimental heart drug fails in late-stage trial

Ionis Pharmaceuticals and partner Novartis' experimental drug to lower ​high levels of a cholesterol-carrying particle ‌in heart patients failed in a late-stage trial, the companies said on Friday. Ionis, Novartis' key experimental heart drug fails in late-stage trial.

Why it matters. This failure impacts the development pipeline of major pharmaceutical companies and delays new treatment options for patients with high cholesterol-carrying particles.

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